2,918 Founding Engineer jobs
Founding engineer roles building the first product at early-stage startups.
Member of Technical Staff
Early-career-to-mid full-stack engineer on a small team building AI-powered browser automation for healthcare workflows. Day to day: improve automation-building agents, scale worker orchestration and job queues on AWS, and ship APIs, SDKs, and observability tooling across the stack.
Founding Engineer
Founding engineer at Clera, an early-stage San Francisco startup building a cloud-first platform for orchestrating coding agents. You'll build the orchestration engine, run agent workloads across cloud, bare-metal, and customer infrastructure, and develop desktop, web, and mobile interfaces alongside the founders.

Software Integration Engineer - HIL
A hands-on role on Stoke Space's software integration team, owning the software configuration and lifecycle of HIL rigs and ground support equipment for the Nova reusable rocket. Day to day the engineer writes Rust/Linux tooling, automates ground networks and test hardware, and physically builds and troubleshoots racks, checkout carts, and avionics integration.

Vehicle Software Engineer – Rust Controls
Builds a Rust-based automation framework that lets Stoke Space teams compose vehicle and ground control behavior for benchtop checkouts, engine hotfires, and flight of the Nova reusable rocket. Day-to-day work spans Rust and Python, distributed software-hardware control abstractions, guardrails, tests, and hardware test support.
Software Engineer, AI Developer Platform
Backend engineer at Mirage (an AI video company) owning the path from commit to production: rebuilding CI/CD, safe deployments, agent sandbox environments, AI code review, and security pipelines to handle AI-agent-scale code volume, while shipping features across its AI video products and developer platform. In-person at NYC HQ.
Software Engineer II, BI
Develop and lead end‑to‑end features for a healthcare BI platform, designing scalable cloud data services, APIs, ETL pipelines, and interactive React dashboards, using Python (FastAPI/Flask/Django), AWS, SQL/NoSQL, and CI/CD.
Sr. Software Engineer
Build and ship full-stack healthcare automation tools using AI/ML, React, Python/Java, and cloud services to streamline prior authorization and care journeys.
Senior Software Engineer
Senior full-stack engineer at Droxi, a healthcare startup whose AI assistant relieves EHR inbox overload for clinicians. Day to day you build Python back ends and Angular front ends, architect databases supporting ML/LLM features, and collaborate with data scientists and product teams. Hybrid role based in Ramat Gan (~3 days/week in office).
Founding Engineer
Founding engineer at Bayworks (YC F26), a startup capturing voice and video from auto technicians to turn every repair into structured ground truth. You'd build pipelines and AI models in Python/SQL, create evals for LLM/speech models, and ship production systems for dealerships.
Principal Software Engineer, Instrument Simulations
Principal Software Engineer designs and leads development of high-fidelity lab automation simulations and integration layers for AI-driven robotic systems, mentoring a small team in Cambridge, MA.
Senior Automated Systems Engineer
Hands-on automation engineer at an AI-driven science startup in Cambridge, MA, designing, building, and maintaining high-throughput automated lab workcells for synthesis and characterization workflows. Bridges science, hardware, controls, and software using Python, CAD/3D printing, sensors, machine vision, and robotics.
Senior Software Engineer, App
Senior software engineer on LILA Sciences' Application team, building the full-stack, AI-native platform that lets scientists collaborate with AI agents — designing UI and APIs, scaling SQL/NoSQL/vector databases, and running workloads on AWS and Kubernetes to connect AI to automated lab workflows.
Senior Software Engineer, Data
Senior backend software engineer on LILA Sciences' Data Platform Team, building the data backbone of its autonomous 'AI Science Factory' — high-performance APIs, SQL/NoSQL/vector database systems, workflow orchestration, and cloud infrastructure (AWS, Kubernetes) that turn lab and instrument data into faster scientific discovery.
Software Engineer, AI Platform
Software engineer building the ML libraries, CI/CD pipelines, and data ingestion tooling that power LILA Sciences' AI-driven research platform, working alongside machine learning engineers and researchers. Core stack: Go/Python, Ray, Kubernetes, ArgoCD, and GitHub Actions.
Senior Software Engineer, Operations Research
Senior Software Engineer designs and builds backend systems, APIs, and data pipelines for AI-driven lab orchestration and robotics workflows, using Python, AWS, Kubernetes, and operations research tools.
Senior Software Engineer, Scientific System of Record
Senior full-stack engineer on LILA Sciences' Scientific System of Record team, building the systems that capture experiment plans, lab execution, and results. Day-to-day spans React/TypeScript UIs, Python backend services and APIs, data modeling across SQL/NoSQL/vector stores, and deployment on AWS and Kubernetes.
Staff/ Principal Software Engineer, Scientific System of Record
Lead architecture and development of an AI-driven scientific platform that integrates lab workflows, data capture, and analytics, using TypeScript, React, Python, and modern cloud infrastructure.
Principal Software Engineer, App
Designs and builds the AI-native application layer of LILA's scientific discovery platform: full-stack UIs and APIs (React, TypeScript, FastAPI, Python), database architecture across SQL/NoSQL/vector stores, and AWS/Kubernetes infrastructure so researchers can collaborate with AI agents from hypothesis to experiment.
Senior II/ Staff Software Engineer, Platform Operations
A senior/staff engineer on the Platform Operations team who designs, builds, and operates production backend services, internal tools, CI/CD and deployment workflows, and reliability systems. Core stack includes Python/TypeScript/Go, AWS, Kubernetes, and agentic AI coding tools, working alongside ML and scientific teams.