Sr. Clinical Development Director
Description
Let’s build the future of medicine - together.
Remote| Full-time | $340,000–$380,000
YOUR ROLE
As a Sr. Clinical Development Director at Enveda, you won’t be working on another me-too drug. You’ll be working on a first-in-class opportunity with broad potential across metabolism and autoimmune disease, and it's one of the most exciting bets in our pipeline. You will own the core clinical development plan, design the first-in-human program, and build the path that turns a novel mechanism into a potentially transformational medicine in two therapeutic areas. This is a critical leadership role on the Asset team, where you will have a significant impact on its direction and success while collaborating with some of the brightest minds in the industry.
WHAT YOU'LL DO
- Build the clinical development plan and first-in-human strategy from the ground up
- Design the Phase 1 protocol: dose, endpoints, population, pharmacodynamic readouts, and the design nuance of testing across two therapeutic areas, plus the operational realism to make it run
- Shape the translational and biomarker strategy that turns a preclinical mechanism into a credible human proof-of-mechanism readout
- Support the path to IND and the early regulatory strategy behind it
- Run Advisory Boards that produce decision-grade insight and genuinely change how we approach trial design and next steps
- Build the KOL and site network ahead of the clinic, so we're ready to move when the study opens
- Excite thought leaders, physicians, PIs, and patients about the opportunity in metabolism and autoimmune disease
- Contribute to the broader platform narrative for investors and partners where scientific credibility is on the line
WHAT WE'RE LOOKING FOR
- MD, with credentials that add actual and perceived credibility to the program
- Live, warm global KOL and site network in autoimmune disease (metabolic disease as well is a plus)
- Track record of taking assets into the clinic and landing non-trivial first-in-human and early-phase programs. Bonus points for at least one 'not just another X study' where design creativity was the unlock
- First-hand experience designing and running early clinical development, particularly proof-of-mechanism studies in immune-mediated disease
- Comfortable owning translational and pharmacodynamic strategy, not just trial logistics
- Clinically creative and unlocked by clinical depth; strong strategic and scientific judgement
- An undisputed champion for patients, someone willing to go to bat and change the paradigm, not just add another entry to it
- The person colleagues call when they want a straight answer; well-regarded in the community in a substantive, not just social, way
- Entrepreneurial by nature: comfortable with ambiguity, energized by building, motivated by impact over process
- Ego-lite, Enveda culture: collaborative, direct, gets the work done without needing the spotlight
ABOUT ENVEDA
We're a clinical-stage, AI-enabled biotech discovering medicines from nature four times faster than the industry standard. We recently raised $311M in a Series E, bringing total funding to over $845M, and doubled our valuation to $2B. We now have three oral medicines in the clinic, including our lead drug, ENV-294, in Phase 2 trials for eczema and asthma. Forbes named us one of America's Best Startup Employers, and Newsweek recognized us as a Top 100 Most Loved Workplace. We're still early, and most of the best work is ahead of us.
Benefits (Starting Day 1): Medical, dental, and vision covered at 90%, 401(k) with company match, flexible PTO and a company-wide weeklong recharge break, adoption assistance
Our Process: We move fast and respect your time. Typically: a recruiter screen → hiring manager conversation → work sample, technical interview, & culture interview.
Our Values: Curiosity | Agency | Journey | Charity | Unity
Enveda is protecting Job Seekers
We care deeply about creating a safe, respectful experience for every applicant, so we wanted to share a few guidelines to help you spot anything that doesn’t feel right.
- You’ll always meet real Enveda team members through video or in-person conversations before receiving an offer.
- All communication from us will come from an @enveda.com or @envedabio.com email address.
- We’ll never ask you to purchase equipment, send money, or share sensitive banking details as part of any step in our recruiting process.
If something feels off or you’re unsure whether a message is truly from Enveda, please reach out at anytime at recruiting@enveda.com.
As published by lever · 8 questions · 2 written answers
Basics
Resume/CV, Full name, Pronouns, Email, Phone, Current location, Current company, LinkedIn URL, GitHub URL, Other website
Pick from a list (6)
- (GDPR/CCPA) - Your personal data will be processed for recruiting related activities, which include setting up and conducting interviews and tests for applicants, evaluating and assessing the results thereto, and as is otherwise needed in the recruitment and hiring processes. Such processing is legally permissible under the GDPR (General Data Protection Regulation) and CCPA (California Consumer Privacy Act) as necessary for the purposes of the legitimate interests pursued by Enveda, which are the solicitation, evaluation, and selection of applicants for employment. Your personal data will be retained by Enveda as long as we determine necessary to evaluate your application for employment. You have the right to request access to your personal data, to request that your personal data be rectified or erased, and to request that processing of your personal data be restricted. optional
- (Transcription) - Candidate experience will always be top priority for Enveda. We would like to offer you the opportunity to have your virtual interviews transcribed. This will allow your interviewer to spend less time notetaking and more time being present and engaged with you. In addition, transcriptions may help to expedite feedback so you will know what is happening with your candidacy sooner. You can opt out at any time which will not affect your candidacy. Opting in enables you to request a copy of the transcription. optional
- How many years of experience do you have leading early phase clinical development programs, including first-in-human or proof-of-mechanism trials?
- Which best describes your experience in Clinical Development track record of taking assets into the clinic? You may select more than one answer. optional
- Select all of the following areas in which you have direct clinical development experience. optional
- Which best describes the breadth of your current global KOL and site network in autoimmune disease?
Written answers (2)
- Describe your experience in designing early phase clinical trials, including first-in-human or proof-of-mechanism studies in immune-mediated disease, and the role you played in shaping dose, endpoints, population, and pharmacodynamic readouts.
- Detail a situation where you exhibited agency by taking ownership of ambiguity to build a clinical trial design that broke from convention, and explain how that design decision changed the direction or outcome of the program.