Clinical Informatics Analyst - Institute for Genomic Health (On Site - New York, NY)

Join the Institute for Genomic Health (IGH) at the Icahn School of Medicine at Mount Sinai and play a critical role in advancing precision medicine at one of the nation’s leading academic health systems. As a Clinical Informatics Analyst, you will help enable cutting-edge research in genomic medicine that bridges discovery and patient care. This is a highly collaborative role at the intersection of data science, genomics, and clinical research.

• Enable high-impact research: Partner with students and investigators to access, interpret, and analyze large-scale clinical and genomic datasets, accelerating translational discoveries.
• Build and optimize data infrastructure: Maintain and enhance centralized data resources, documentation, and metadata systems to ensure efficient, scalable, and reproducible research.
• Drive advanced phenotyping: Develop and implement robust phenotyping algorithms using validated frameworks; harmonize clinical ontologies to support cross-study analyses.
• Support genomic analyses: Contribute to genetic data quality control and preparation for downstream analyses, including genome-wide association studies (GWAS).
• Lead and coordinate collaborations: Serve as a key liaison across multidisciplinary teams.
• Shape research strategy and execution: Contribute to study design, data extraction, statistical analysis, and manuscript development for high-impact publications.
• Strengthen operational excellence: Support onboarding, contracting, and compliance processes; lead or facilitate project meetings; and develop standard operating procedures to streamline workflows.
• Innovate with emerging technologies: Evaluate and integrate cutting-edge tools, including AI/LLM-based approaches, to enhance phenotyping and data analysis capabilities.
• Amplify scientific impact: Contribute to grant proposals, presentations, and dissemination of findings at institutional and national levels.

• BA or BS degree required; MS or doctoral degree in Clinical Informatics preferred.
• 5 years of experience in a related field.
• Significant expertise with programming and statistical software experience in R, Python, SQL
• Familiarity with modern database design and operation
• Familiarity with clinical informatics frameworks and Electronic Health/Medical Record data types and ontologies, including ICD-9/10, LOINC, RxNorm, UMLS, CPT codes, etc.
• Familiarity with EPIC EHR systems (Clarity, Caboodle) is a strong advantage
• Strong communication and presentation skills.

Please note this is an onsite position at the Icahn School of Medicine at Mount Sinai in New York, NY.