Data Science Intern

Intern, Discovery Data Science (Project: Spatial Transcriptomics for Antibody Based Drug Discovery and Development in Solid Tumors) Solliciteer nu Does this inspire you and feel like a fit? Then we would love to have you join us! We are posting several projects within our Utrecht Genmab site, each with its own research focus, recruitment team, and selection process. Please take time to explore the available projects and apply to a maximum of two that best match your interests and skills. If you apply to two, include the project titles in order of preference in both motivation letters , with a brief explanation of your interest in each. This helps our teams understand your preferences throughout the separate selection processes! The Role How can the location of a cell within a tumor help us discover new therapeutic targets? Join Genmab as a Data Science intern and explore how spatial transcriptomics can support the discovery of antibody-based treatments. Bulk and single-cell RNA sequencing help us understand which cells are present and which genes they express. Spatial transcriptomics takes this further by showing where those cells are located within the tissue. This gives us a richer picture of the tumor microenvironment and new opportunities to investigate potential therapeutic targets. Working closely with our Target and Product Discovery teams, you will analyze spatial transcriptomics data from solid tumors and develop methods to turn complex datasets into meaningful biological insights. You will explore questions such as: What makes a target's expression specific to a tumor? How might its location influence accessibility to an antibody-based therapeutic? And what can spatial data tell us that bulk and single-cell approaches cannot? You will gain hands-on experience in analytical method development, data analysis, project planning, and presenting your findings to scientific colleagues. With the research questions still t...