（高级）工艺研究员，小分子CMC DS（博士岗）

Job Description:

The position is a scientific role in the CMC drug substance function, which provides scientific research and project management support for small molecule projects. The responsibilities include below items.

• Design and evaluate synthesis route under supervision.
• Design and execute experiments to optimize manufacture process independently. Design and execute salt/polymorph screening of small molecule projects independently.
• Identify and resolve scale-up challenges under supervision through critical evaluation of process and analytical data in drug substance manufacturing.
• Support technical platform establishment by providing scientific inputs through literature search,
• Act as the drug substance representative under supervision, to closely work and communicate within CMC team.
• Manage drug substance manufacture in CMO partners under supervision, to deliver drug substance to meet clinical/commercial demand.
• Communicate effectively across organizational interfaces. Lead the transfer of know how to other departments or external contractors.

Job Requirements:

• PhD degree, major in organic chemistry, medicinal chemistry, or related.
• Good learning agility, flexible and comfortable in a fast pace working environment, to effectively and accurately present data to peers, management, and external partners.
• Strong passion and exploration desire in science. Demonstrated independent scientific thinking and creative problem-solving skills in trouble shooting of drug substance process development.
• Good communications skills to work collaboratively with peers across multiple areas.
• Good understanding to manage drug substance manufacturing, to be able to handle change controls and investigate deviations under supervision.
• Good English language skills is required, to be able to make presentation and have technical discussion in English.