Member of Technical Staff, Science
Summary
LatchBio builds AI biology benchmarks used by frontier labs (Anthropic, xAI) for capability and biosecurity evaluation. This onsite role turns biological domain expertise into benchmark roadmaps designed with engineers, then builds and manages a scientific team; requires deep science + AI-tool experience or strong math/CS training.
Member of Technical Staff, Science
Our mission is to advance humanity's ability to engineer biology. We approach this by understanding and improving AI’s application to biology across basic research, drug discovery, and biosecurity. We are a team of engineers, scientists, and operations specialists who are driven by improving capabilities and interpretability. Some of our work is showcased on .
About this role. You’ll turn your understanding of a biological domain into a roadmap of benchmarks and design them with engineers. You’ll then build and manage your own scientific team using your network and internal talent infrastructure.
You have
(1) deep scientific expertise and experience using AI tools
(2) or strong coursework in math/CS and experience working with scientists
This is a high-intensity, founder-type role. Our Members of Technical Staff have built companies, run drug programs and scaled complex technical projects.
Projects you might work on:
- Design benchmarks with engineers and scientists, from selecting scientific questions and datasets to developing reliable graders.
- Work with engineers on large-scale computing and AI inference infrastructure to evaluate models and investigate their failures.
- Research new methods for evaluating scientific capabilities and measuring improvements from training.
- Work with our internal data generation and drug development teams to build tasks around real experiments and research decisions.
How we work. Our MTS team works in person in Mission Bay, San Francisco. We keep meetings to a minimum and are flexible about when you arrive or leave. Tight deadlines and customer commitments sometimes require late hours.
Our work in use. Frontier AI labs use our benchmarks to assess biological capabilities and safeguards. Our work appears in research announcements and model cards, including:
Anthropic: Claude Fable 5.1 and Mythos 5.1 system card
Anthropic: Claude Opus 5.5 system card
Anthropic: Advancing Claude in healthcare and life sciences
xAI: Grok 4.7 model card
xAI: Biosecurity at the frontier
Hiring Process.
Our process is typically completed within two weeks.
Round 1: Introduction
Round 2: Technical project matching
Round 3: Take-home evaluation project (~2 hours)
Round 4: Technical interview / live engineering session (1 hour)
Round 5: Paid onsite project and presentation (2–3 days)
Offer
Compensation & Benefits
350K-500K+ OTE
Equity
Unlimited PTO
Health, dental and vision insurance fully covered
Visa sponsorship and relocation assistance
401(k)
Office in Mission Bay, San Francisco
Lunch and dinner provided
Skills
As published by ashby · 7 questions · 2 written answers
Basics
Name, Email, Resume
Short answers (4)
- Phone Number optional
- LinkedIn URL
- Will you now or in the future require visa sponsorship?
- What is your earliest available start date? optional
Pick from a list (1)
- What is your current geographic availability for this role?
Written answers (2)
- Tell us about a space, event, or community you built or ran yourself. What did you start with, what did you create, and how did you know it was working? optional
- Describe the best office or team event you’ve ever been part of (or organized). What specifically made it great, and what would you steal from it for a fast-growing startup? optional
