Molecular Biologist / Research Scientist
Summary
Designs and runs automated continuous evolution experiments in yeast, including library construction, selection strategies, and flow cytometry readouts.
The role
We are building an automated biology platform and, and we are looking for a molecular biologist / research scientist to handle the core wet lab work: selection design, library construction, and readouts.
Responsibilities
Run end to end workflows, library through selection to characterized hits
Design selection strategy: stringency schedules, bottlenecks, counter-selections
Design FACS sorting and screening strategies, and interpret population trajectories across rounds
Must-haves
Cell culture: hands-on experience, ideally with yeast.
Molecular cloning: fundamentals (PCR amplification, Gibson assembly, Golden Gate assembly, transformations); experience with sequencing services.
Flow cytometry/FACS: gating strategies, staining, sample loading.
Nice-to-haves
Yeast genetics and surface display · OrthoRep or other continuous hypermutation systems · phage display or PACE · SPR/BLI · NGS library prep and analysis · protein expression and purification · Opentrons, Hamilton, Tecan, or eVOLVER-class hardware.
If you have never worked in yeast, apply anyway. We would rather hire for selection judgment and long-run discipline, and teach the organism.
As published by ashby
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