Monolix, Nonmem, Phoenix WinNonlin

Key Responsibilities

• Install, configure, and validate scientific software on Domino Data Lab platform
• Set up and maintain Monolix, NONMEM, and other pharmacometric modeling tools
• Create and manage custom compute environments and Docker images for scientific applications
• Ensure software configurations meet GxP compliance and validation requirements
• Develop installation documentation and user guides
• Troubleshoot software installation and configuration issues
• Collaborate with platform administrators and scientific users to optimize software performance
• Manage software licensing and version control
• Support software qualification and validation activities

Required Skills & Qualifications Statistical modeling tools

• 5+ years of experience in scientific software administration or computational sciences
• Hands-on experience configuring pharmacometric software (Monolix, NONMEM, Phoenix WinNonlin)
• Proficiency with statistical computing software (R, Python, SAS, MATLAB)
• Experience with Domino Data Lab or similar data science platforms
• Strong Linux/Unix system administration skills
• Knowledge of containerization (Docker) and environment management
• Understanding of software validation in regulated environments
• Scripting skills (Bash, Python) for automation
• Problem-solving abilities for complex software dependencies

Preferred Qualifications

• Background in pharmacokinetics/pharmacodynamics (PK/PD) or pharmacometrics
• Experience in pharmaceutical industry with GxP systems
• Familiarity with additional scientific software (Berkeley Madonna, SimCYP, GastroPlus)
• Knowledge of high-performance computing environments
• Experience with Conda, virtual environments, and package management