Research Assistant, Upstream Process Development
This position requires at least a Bachelors degree in Biochemistry, Molecular Biology, Biochemical Engineering, or related area. Knowledge of mammalian cell culture, as well as related analytical methods, and aseptic handling techniques is essential. Knowledge of bacterial fermentation is a plus.
ESSENTIAL DUTIES AND RESPONSIBILITIES
Performs laboratory experiments related to development of robust upstream processes for manufacturing of human therapeutic proteins produced in recombinant mammalian cells and bacteria
Designs, executes, and analyzes experiments at laboratory scale, including shake flasks, spinner tubes, scale down bioreactor systems (Ambr) and bench top reactors (Applikon).
Develops and characterizes scaled-down models for upstream unit operations.
Possesses knowledge of and experience with cell culturing, handling, counting, media preparation, ELISAs, pipetting, centrifugation, filtration, etc.
Responsible for accurate laboratory data entry, lab maintenance and upkeep, and report writing.
Supports identification and optimization of alternative laboratory methods and/or equipment to improve work efficiency and throughput.
Retains an up to date knowledge of analytical techniques and relevant scientific literature.
Responsible for accurate laboratory data entry, maintenance of necessary documentation and day to day operations.
Keeps Team Leader & Project Manager informed on a regular basis on project status and any circumstances which may alter project scope or established timelines.
EDUCATION AND EXPERIENCE
BS in Cell Biology, Molecular Biology, Biochemistry, or other relevant area
Experience performing a variety of assays including ELISA, IEF gels, PAGE gels and Western blots preferred.
Knowledge of technologies related to protein expression.
Experience in cell culture process development and Design of Experiment (DOE) a plus.
DESIRED KEY COMPETENCIES
Theoretical knowledge and some practical experience in cell culture as demonstrated by presentations and/or publication record.
Participates in solving difficult and complex technical problems.
Good communication and presentation skills.
Team player.
Develops solutions to a variety of complex problems. Solutions are imaginative, practical and consistent with organization objectives.
Plans schedules and lab activities to accomplish objectives.
Ability to track and execute on multiple projects simultaneously.
Creative, actively participate in idea generation.
Our Company offers excellent benefits including medical, dental, vision, life, short and long term disability plans, 401k, FSA, vacations, paid holidays and health club reimbursement.