Research Scientist – Nucleic Acids Chemistry R&D
Centrillion Biosciences is seeking a creative, energetic, resourceful organic chemist to join a multidisciplinary research team developing new technologies for nucleic acid sequence analysis.
Duties:
- Plan and execute applied research experiments involving:
- Synthesis, modification and characterization of modified nucleotides, nucleoside polyphosphates and oligonucleotides
- Preparation of fluorescent dye conjugates of nucleotides and oligonucleotides.
- Materials modification and characterization for solid phase synthesis
- Collaborate with and/or supervise other scientists & engineers on joint projects.
- Documentation of experimental work; analysis of data; documenting and presenting results
- Preparation of written methods and SOPs
- Operation and maintenance of laboratory & analytical equipment
- Support R&D and Pilot Manufacturing Operations and QC
- PhD in organic chemistry, with extensive training and practical laboratory experience in organic synthesis, physical organic and bioorganic chemistry.
- Experience with nucleoside, nucleotide, and solid-phase oligonucleotide synthesis.
- Experience preparing fluorescent dye conjugates of nucleotides and oligonucleotides.
- Proficiency in the use of methods of instrumental chemical analysis, such as NMR, HPLC, MS, FTIR, is essential.
- Working knowledge and practical experience with polymer and surface chemistry is strongly desired.
- Demonstrated ability to plan and execute independent and collaborative research projects.
- Demonstration of goal-oriented, hands-on and innovative approach to problem solving.
- Excellent written and oral communication skills.
- Co-authorship on one or more publications in peer-reviewed scientific journals.
- She/he will be required to develop additional competencies, and apply practical skills and knowledge to solving a variety of applied scientific and technical problems.
All your information will be kept confidential according to EEO guidelines.