Scientist II / Mass Spectrometry Automation Engineer
Posted Updated 2
views
Description
Scientist II / Mass Spectrometry Automation Engineer
Hourly Rate: $60 - $64/hr with medical benefits available at a cost
Contract Length: 1 year initial contract with possibility of extension
Location: South San Francisco, CA
Work Schedule: 100% onsite, Monday – Friday
Orion Project Services is teaming up with a market leading pharmaceutical company to find a Scientist II / Mass Spectrometry Automation Engineer for a one-year contract in South San Francisco, with the possibility of extension.
In this onsite role, you’ll support discovery research by producing and characterizing biologics such as monoclonal antibodies and multispecific proteins. You’ll conduct LC/MS analyses, maintain and troubleshoot mass spectrometry equipment, coordinate protein production with external partners, and share findings with a collaborative, multidisciplinary team. You’ll also have the opportunity to contribute to method development and explore new bioanalytical technologies.
Job Description:
Discovery Biotherapeutics and Genetic Medicine (BGM) within a market leading pharmaceutical company is seeking a highly motivated scientist to join the Biotherapeutics group at their Bay Area (ABA) site in South San Francisco.
This role offers a unique opportunity to contribute to various Discovery Research Therapeutic Areas (TAs) and projects by providing production and analytical characterization of biologics and biopharmaceutical products, such as monoclonal antibodies, multi-specifics, and other antibody-like formats. As part of our team, your work will drive the discovery and development of next generation biologics through production and interrogation of protein attributes.
Key Responsibilities:
People are our business worldwide
Orion Group was founded in 1987 and is now one of the largest, independent, international recruitment companies. We have a network of 200 employees working from 24 offices, delivering a range of services – Talent Acquisition, Recruitment Outsourcing Services, Retained Search, Global Workforce Solutions, Completions & Commissioning and Materials Management – across 68 countries. As a global leader in workforce solutions, we recruit personnel across the Engineering & Technical, Office & Commercial, Scientific and Skilled Trades disciplines, for sectors including Oil & Gas, Life Science, Power & Utilities, Constructions & Infrastructure, Manufacturing and Renewables.
Hourly Rate: $60 - $64/hr with medical benefits available at a cost
Contract Length: 1 year initial contract with possibility of extension
Location: South San Francisco, CA
Work Schedule: 100% onsite, Monday – Friday
Orion Project Services is teaming up with a market leading pharmaceutical company to find a Scientist II / Mass Spectrometry Automation Engineer for a one-year contract in South San Francisco, with the possibility of extension.
In this onsite role, you’ll support discovery research by producing and characterizing biologics such as monoclonal antibodies and multispecific proteins. You’ll conduct LC/MS analyses, maintain and troubleshoot mass spectrometry equipment, coordinate protein production with external partners, and share findings with a collaborative, multidisciplinary team. You’ll also have the opportunity to contribute to method development and explore new bioanalytical technologies.
Job Description:
Discovery Biotherapeutics and Genetic Medicine (BGM) within a market leading pharmaceutical company is seeking a highly motivated scientist to join the Biotherapeutics group at their Bay Area (ABA) site in South San Francisco.
This role offers a unique opportunity to contribute to various Discovery Research Therapeutic Areas (TAs) and projects by providing production and analytical characterization of biologics and biopharmaceutical products, such as monoclonal antibodies, multi-specifics, and other antibody-like formats. As part of our team, your work will drive the discovery and development of next generation biologics through production and interrogation of protein attributes.
Key Responsibilities:
- Conduct mass spectrometry analyses for comprehensive characterization of biologics and biotherapeutics, including intact, reduced, and subunit approaches.
- Ensure the optimal functioning of LC/MS equipment through routine maintenance and effective troubleshooting.
- Design and execute production of biotherapeutic proteins to external CRO vendors, provide guidance on desired product quality attributes, then deliver the results of the production to our therapeutic partners.
- Contribute to team discussions, share valuable insights, and present experimental findings and progress updates to colleagues and stakeholders.
- Collaborates with MS experts across our Research & Development Division to assess and implement new bioanalytical technology.
- Independently and autonomously perform laboratory research and method development with minimal supervision, demonstrating high productivity and scientific initiative.
- BS, MS, or PhD in chemistry, biochemistry, or related discipline with typically 7+ (BS), 5+ (MS), or 0+ (PhD) years of relevant experience.
- Demonstrated hands-on expertise with various mass spectrometry platforms, including Waters Xevo G2-XS QToF, along with proficiency in MS workflows for protein characterization and the use of MS software for analyzing both routine and complex datasets.
- Proficiency in data processing and bioinformatic and statistical workflows (e.g., Protein Metrics, Biosphere, Waters Connect, UNIFI)
- Proven experience in the application of LC/MS analyses for interrogation of monoclonal antibodies, multispecific biologics, and protein therapeutics to provide sequence verification, post-translational modification, desired/expected chain pairing, and identity of DLP profile.
- Experience with coding/programming (e.g., Python, R, or relevant scripting languages) and in developing automated data workflows or solutions.
- Experience with chromatography and purification systems (protein A/G, AEX, SEC, mixed-mode with AKTA systems), and analytical instruments (Agilent HPLC, Waters UPLC and LC/MS, CE-SDS, SDS-PAGE) is a plus
- Goal-oriented team player with excellent verbal and written communication skills, a strong positive attitude, and the ability to thrive in a fast-paced, multidisciplinary environment.
People are our business worldwide
Orion Group was founded in 1987 and is now one of the largest, independent, international recruitment companies. We have a network of 200 employees working from 24 offices, delivering a range of services – Talent Acquisition, Recruitment Outsourcing Services, Retained Search, Global Workforce Solutions, Completions & Commissioning and Materials Management – across 68 countries. As a global leader in workforce solutions, we recruit personnel across the Engineering & Technical, Office & Commercial, Scientific and Skilled Trades disciplines, for sectors including Oil & Gas, Life Science, Power & Utilities, Constructions & Infrastructure, Manufacturing and Renewables.