Scientist/Senior Scientist, In vitro & Preclinical Translational Research
We are seeking a highly motivated Scientist/Senior Scientist with strong expertise in both in vitro and in vivo translational studies for preclinical and IND-enabling research programs. This role is ideal for a PhD- level/ Masters level scientist with strong hands-on laboratory experience and a working understanding of animal research supported translational studies, particularly in oncology, biologics, or antibody-drug conjugates (ADCs). The incumbent works cross-functionally with internal departments and external resources on in vitro and in vivo translational research related issues. The Scientist/ Senior Scientist supports adherence to relevant regulatory requirements and company Standard Operating Procedures (SOPs) as appropriate.
Job Responsibilities:
- Design, execute, and analyze cell-based and biochemical assays to evaluate target biology, mechanism of action, and compound/biologic efficacy.
- Support and/or conduct rodent (mouse) in vivo studies in compliance with IACUC and institutional guidelines.
- Perform mouse handling, dosing (e.g., IV, IP, SC, PO injections), blood collection, tissue harvesting, and necropsy.
- Assist with study planning, execution, and data analysis for pharmacology, efficacy, PK/PD, and tolerability studies.
- Document study outcomes and contribute to study reports, presentations, and regulatory-supporting materials.
- Maintain accurate experimental records and analyze datasets using appropriate statistical methods.
- Troubleshoot assays and contribute to continuous method improvement.
- Perform other tasks and assignments as needed and specified by management.