Senior Manager, ARD Instrument Systems
Description
Use Your Power for Purpose
At Pfizer, our purpose is to deliver breakthroughs that change patients' lives. Central to this mission is our Research and Development team, which is dedicated to translating advanced science and cutting-edge technologies into the therapies and vaccines that matter most. Whether you are involved in discovery sciences, ensuring drug safety and efficacy, or supporting clinical trials, you will leverage innovative design and process development capabilities to accelerate the delivery of best-in-class medicines to patients around the globe.
What You Will Achieve
The Manager, Instrument Systems is responsible for personally conducting while also leading a team of instrument systems professionals who support the lifecycle management, operational performance, and continuous improvement of Biotherapeutics Pharmaceutical Sciences ARD GxP-regulated laboratory systems. The role ensures that instrument systems remain compliant, reliable, inspection-ready, and aligned with business and regulatory requirements while enabling efficient scientific and operational execution.
This position provides direct oversight on the execution, strategic and day-to-day leadership for instrument systems operations, data integrity oversight, and cross-functional stakeholder engagement. The manager is accountable for prioritizing team activities, removing barriers, establishing governance, driving standardization, and building organizational capabilities that support sustainable business growth and operational excellence.
The role serves as a key liaison between Quality, Global Workplace Experience, Digital, Validation, and Scientific functions to ensure instrument-related risks are proactively managed, regulatory requirements are met, and continuous improvement opportunities are identified and implemented.
Role Responsibilities
- Lead and develop a team responsible for instrument systems lifecycle management, ensuring effective prioritization, resource allocation, performance management, and talent development.
- Provide strategic oversight of instrument systems compliance, data integrity, computerized system controls, and adherence to applicable GMP, GxP, regulatory, and company requirements.
- Establish and maintain inspection-ready processes, ensuring support for internal audits, regulatory inspections, quality assessments, and remediation activities.
- Drive governance and oversight of instrument-related quality systems, including CAPAs, changes, risk assessments, and life cycle documentation.
- Partner with Quality, GWE, Digital, and BTx ARD organizations to prioritize work, resolve issues, remove roadblocks, and ensure business continuity.
- Develop and maintain procedures, standards, work practices, and documentation supporting the instrument systems program and compliance framework.
- Lead training strategy and competency development for instrument systems personnel, ensuring knowledge transfer, qualification, and ongoing capability building.
- Identify, prioritize, and implement continuous improvement initiatives that enhance compliance, reliability, system performance, user experience, efficiency, and scalability across the instrument systems organization.
Here Is What You Need (Minimum Requirements)
- BS degree in Biology, Chemistry, or related field with 6+ years of experience in a GMP laboratory or similar field; MS degree with 5+ years, or PhD with 1+ years
- Significant experience supporting regulated laboratory, manufacturing, or quality environments.
- Demonstrated leadership experience managing technical, quality, compliance, or instrument systems teams.
- Experience with regulated computerized systems, validation, and data integrity programs.
- Experience supporting audits/inspections on the topic of instrument lifecycle.
- Experience implementing operational excellence and continuous improvement initiatives.
- Strong understanding of pharmaceutical, biotechnology, or regulated healthcare environments.
Bonus Points If You Have (Preferred Requirements)
- Experience supporting research, development, laboratories, quality, manufacturing, or technical organizations.
- Experience leading enterprise compliance, quality transformation, governance, or continuous improvement initiatives.
- Experience supporting digital quality transformations, eQMS implementations, or AI-enabled compliance solutions.
- Experience partnering with Quality Assurance, GWE, and Digital.
- Demonstrated success leading organizational change and capability-building efforts.
PHYSICAL/MENTAL REQUIREMENTS
Position requires occasional light lifting and periods of standing, sitting or walking.
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Some occasional travel to other Pfizer sites is possible.
Additional Information:
- Work Location Assignment: On Premise
- Last Day to Apply: November 2, 2026
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.
Research and Development