Senior Manager, Biostatistics (Late Stage Oncology) (m/f/d)
Description
The Position
Please note that this position is primarily based in France, with Germany as an alternative location. This position leads complex studies in study design, statistical analysis, and the interpretation of results with some supervision. The position contributes to specific aspects of drug development plans with minimal supervision and to documents submitted to Health Authorities globally with some supervision. It also guides contract research organization (CRO) programmers and statisticians in preparing analysis files and performing statistical analyses. Additionally, the position interacts with study teams, as well as statisticians and programmers at CROs. The position works under some supervision to solve complex study-related problems.
Roles and Responsibilities
- Protocol Development, Case Report Form (CRF; review), Statistical Analysis Plan (SAP), Statistical Analysis, Results Interpretation, and clinical study report (CSR):
- Leads statistical activities for complex studies including study design, protocol development, CRF review, SAP development, analysis files development, statistical analysis accuracy validation, results interpretation and CSR input and review.
- Acts as main statistical contact for the assigned studies and projects.
- Provides guidance to study team on all aspects of statistical activities; collaborates closely with data manager to ensure high quality data.
- Drug Development Strategy: Provides input to multiple aspects of the development plan to ensure the study designs at each phase of the development are scientifically sound, can fulfill regulatory requirements and deliver the pre-specified product profile.
- CRO / Vendor Oversight: Review CRO/vendor proposal and budget. Establishes procedures through regular interaction, setting expectation on deliverables and timelines to guide CRO biostatistician and statistical programmers on complex studies. Ensures deliverables are accurate and delivered according to the timelines.
- Global Health Authority Interaction / Negotiation: Contributes to documents submitted to Health Authorities globally by providing input for the interaction or by writing the interaction document. May participate in meeting or teleconferences with Health Authorities
- Global BDO Strategy to Improve Drug Development: Primarily participates and may occasionally lead moderately complex initiatives, with some level of supervision, to improve the harmonization and efficiency of drug development which leads to cost savings and shortened timelines for the company.
Personal Skills and Professional Experience
Education Qualifications
- Master's Degree in statistics or biostatistics required
- PhD in statistics or biostatistics preferred
Experience Qualifications
- 8+ years of relevant experience in the pharmaceutical industry with a masters degree required
- 5+ years of relevant experience in the pharmaceutical industry with a PhD preferred
Travel Requirements
Ability to travel up to 10% of the time.