Senior Manager - Corporate Accounting

At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.

We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do.

But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.

Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

Position Summary
The Senior Manager – Corporate Accounting oversees close management and is responsible for the oversight of recording for an assigned portfolio of accounts and accounting areas, and leads a team of accountants. The Senior Manager partners closely with SEC Reporting, Financial Planning & Analysis, Internal Audit, Inside Sales, Legal and Human Resources, and supports the Company's internal control environment as a newly public company.

Job Responsibilities
Financial Close Ownership

• Own the monthly and quarterly close for corporate accounting end to end, including the close calendar, task assignment, and on-time completion within the Company's close
• Review journal entries, account reconciliations, and supporting schedules prepared by the team, confirming that support ties and that conclusions are documented
• Oversee the accounting for an assigned portfolio of accounts and accounting areas, including the related estimates, accruals and judgments
• Partner with SEC Reporting so that close outputs support external filings without rework
• Identify and drive reductions in close cycle time without reducing review quality

Internal Controls & Compliance

• Operate and evidence assigned controls over financial reporting, including reconciliation review, and analytical review controls
• Retain documentation sufficient to support control testing, including information produced by the entity
• Own the standard operating procedures and accounting policies for assigned areas, including drafting them, reviewing them periodically, and updating them as processes or accounting guidance change
• Support Internal Audit and the external auditors through quarterly reviews, the annual audit, and control testing and remediation
• Proactively identify control design gaps in assigned areas and propose remediation

Systems & Process Improvement

• Drive automation and standardization across close and reconciliation processes
• Partner with IT and Financial Systems on ERP enhancements, reporting, and system implementations
• Extend the use of automation and AI-enabled tooling into first-level review, including contract term extraction and analytical review
• Build processes that scale with transaction volume and business complexity

Leadership & Talent Development

• Manage, coach and develop a team of accountants, and set clear accountability and performance expectations
• Raise the technical capability of the accounting team through review, feedback and on-the-job development
• Foster a culture of ownership, documentation discipline, and continuous improvement

Required Qualifications

• Bachelor's degree in Accounting or related field
• CPA required
• Big 4 public accounting experience required, with a minimum of two years
• 7+ years of progressive accounting experience, inclusive of Big 4 public accounting and at least four years with an SEC registrant or comparable public company
• 2+ years of direct people management experience

Preferred Qualifications

• Strong working knowledge of U.S. GAAP and of internal control over financial reporting
• Demonstrated ability to read an executed contract, determine the accounting treatment independently, and document that conclusion in writing
• Advanced proficiency in Microsoft Office Suite, particularly Excel
• Demonstrated ownership of a monthly or quarterly close, including close calendar management and review of work prepared by others
• Strong ERP systems experience; Oracle and BlackLine experience preferred
• Experience in life sciences, healthcare, diagnostics, or other regulated industries
• Experience in a newly public company, including first-year SOX compliance
• Track record of applying automation or AI tooling to accounting review and documentation
• Experience supporting technical accounting memoranda reviewed by external auditors

Physical Demands

• Must possess ability to sit and/or stand for long periods of time
• Must possess ability to perform repetitive motion

Training

• All job specific, safety, and compliance training are assigned based on the job functions associated with this employee.

Other

• At times, may be required to work weekends/holidays.

Conditions of Employment: Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check ( applicable for certain positions) and reference verification.

This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.

Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.