Research Associate II, Bioanalytical
Summary
Develops and runs bioanalytical assays for biologic drug candidates in a lab setting, focusing on protein signaling pathways and supporting preclinical/clinical studies.
At Keros, our mission is to deliver significant clinical benefit to a wide range of patients with disorders that are linked to dysfunctional signaling of the transforming growth factor-beta (TGF-ß) family of proteins. With a focus on developing differentiated product candidates that are designed to alter TGF-β signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. We believe our product candidates have the potential to unlock the full therapeutic benefits of modulating the TGF-β superfamily and provide disease-modifying benefit to patients.
Job Summary:
Keros is seeking a Research Associate II with a working knowledge of large molecule/biologics bioanalytical techniques and laboratory skills. The primary focus will be developing and performing bioanalytical methods for programs in preclinical and clinical development, documenting the methods used, interpreting, and summarizing the data collected. This role, reporting to the Scientist, Bioanalytical will be responsible for activities related to the development, qualification and bio-analysis for non-regulated methods and samples in support of drug candidate development.
This is a full-time laboratory position based in Lexington, MA.
Responsibilities:
- Perform laboratory experiments as directed
- Help to identify and develop novel bioanalytical approaches to address important scientific questions in support of the discovery and development of novel drug candidates
- Collaborate, as needed, with external vendors for the transfer of primarily ELISA/ECL based PK, ADA including Nab assay, and biomarker assays to support development of large molecule drug candidates
- Perform internal testing of preclinical samples
- Maintain inventory of critical reagents for bioanalysis
- Other duties and responsibilities as required by study needs
Qualifications:
- Bachelor’s degree in cell biology, molecule biology, biochemistry, immunology, or related field with 0 to 2 years of relevant experience in an industrial pharmaceutical/biotechnology lab setting
- Experience with immunoassay development and statistical data analysis, such as ELISA, MSD, Pk assays, ADA assays, biomarker assays et al.
- Experience with biomarker methods is a plus
- Excellent attention to details, critical thinking, and data interpretation
- Ability to work with demanding deadlines and in a fast-paced work environment
- Involvement in a high-throughput environment desirable
- Excellent written and verbal communication and documentation skills
This pay range represents the base hourly rate or base annual full-time salary for all positions in the job grade within which this position falls. The actual base salary offer will depend on a variety of factors including experience, education, and other relevant factors.
Our Diversity, Equity & Inclusion Mission Statement: Keros is an inclusive company. We believe that diversity drives innovation. We continue to build an inclusive culture that encourages, supports, and celebrates the diverse voices of our employees. As such, Keros takes a holistic approach in mentoring, coaching, and developing all of our Keros team members.
Keros Therapeutics is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected veteran status, or any other characteristic protected by applicable federal, state, or local law.
Recruitment & Staffing Agencies:
Keros Therapeutics does not accept unsolicited resumes from any source other than the candidate directly. Any unsolicited submission by an agency to Keros is prohibited. Any resume submitted by an agency without a signed contract or expressed consent by a member of the Keros Therapeutics Human Resources Department, will be considered property of Keros Therapeutics, and no fee shall be owed with respect thereto.