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Principal Product Manager
Senior individual-contributor product manager at MCG Health who sets product strategy and owns AI and data products for healthcare from discovery through launch, working with clinical, data science, and engineering teams. Requires 10–15 years of product management experience, ideally in healthcare technology.
Principal Product Manager, Chemistry
Principal Product Manager owning the product strategy for Chemistry workflows, data products, and AI-enabled decision support in oncology drug discovery at Revolution Medicines. Day to day: partner with medicinal/computational chemists and data/ML teams to accelerate the Design-Make-Test-Learn cycle using tools like Benchling, D360, CDD, and modern AI/low-code platforms.
Principal Product Manager
Principal Product Manager in Microsoft's Experiences & Devices Security organization, defining strategy for certificate, secret, and key management plus cryptographic modernization and post-quantum readiness across Microsoft 365 and Azure-scale infrastructure. Hybrid role based in Redmond, WA with 3 days/week in office.
WhereTo - Chef de produit principal - Canada, Télétravail
Senior Product Manager for WhereTo, Flight Centre's AI-powered business travel studio, remote anywhere in Canada (except PEI). Owns the vision, roadmap and full product lifecycle for trip planning and travel operations products serving Corporate Traveller and FCM, working with engineering, UX and marketing.
Principal Product Manager- M365 Core Copilot Infrastructure Team
Principal Product Manager defining the strategy and multi-year roadmap for the LLM platform that powers Copilot AI experiences across Microsoft 365 — focused on reliability, scalability, cost-efficiency, and operational excellence of large-scale AI infrastructure. Requires 10+ years in product management or software development and strong distributed-systems technical judgment.


Principal Product Manager
Principal Product Manager owning Snapdocs' Quality Control product area: setting strategy, roadmap, pricing, and go-to-market for AI-driven automation that helps mortgage lenders review real estate closing documents. Remote US role; base salary varies by zone ($171.5K–$214.5K, or $196K–$245K in SF/Seattle/NYC) plus equity.
Principal Product Manager (MajorClarity)
Principal Product Manager for Edmentum's MajorClarity line: defines portfolio-level product vision and strategy, drives innovation and data-informed discovery, shapes enterprise pricing/packaging and go-to-market, and mentors the PM team. Remote-first edtech company; requires 6+ years of product management experience.
Principal Product Manager, Augmented Memory Grid (AMG)
Own the roadmap for WEKA’s Augmented Memory Grid, optimizing LLM inference performance by offloading KV-cache and integrating with engines like vLLM and NVIDIA Triton.
Principal Product Manager, AI
Senior IC product manager at LTK, a creator-commerce platform, defining AI product strategy: LLM agents, an agent harness, LLM judges, in-house ML models, and a proprietary knowledge graph. Day to day: partner with ML/data science on model capabilities, build rigorous AI evaluation frameworks, and ship AI features for creators, brands, and shoppers.
Principal Product Manager, American Football Products
Genius Sports is hiring a Principal Product Manager to own its American Football product suite — real-time event and statistics feeds, the Performance Studio analytics platform, and next-gen stats/visualizations — serving leagues like the NFL and NCAA plus media and betting partners. The role spans the full product lifecycle at the intersection of computer vision, real-time data collection, and sp
Principal Product Manager
Thoughtworks is hiring a founding Principal Product Manager in Riyadh to lead lean, AI-first multidisciplinary pods for Middle East clients — partnering with C-suite stakeholders across discovery, go-to-market, delivery, and account growth. Requires 8+ years of product leadership with strong commercial, AI, and consultative-selling skills.
Principal Product Manager, Agentic AI Infrastructure
DigitalOcean is hiring a Principal Product Manager to own the strategy and roadmap for a new managed agentic AI infrastructure product line (e.g., Action Gateway, Inference Router). Day to day, they work with agent-native customers and engineering to define services around MicroVMs, sandboxing, tool execution, and observability, shape developer experience, and launch and price new SKUs.
