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22.2K jobs
Hut 8
yesterday

Principal, IT Operations & Infrastructure Engineer

NewBe an early applicant North AmericaPrincipal
United States

Manages and maintains Hut 8's corporate IT infrastructure from its Miami HQ — designing and running servers, networks, and cloud services (Azure/GCP), administering Microsoft 365 and Active Directory, monitoring performance and security, and supporting end users. Core stack includes Windows/Linux, VMware/Hyper-V, Fortinet, and PowerShell/Python scripting.

Active Directory AI Azure Cloud Fortinet +9 skills
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Apptronik
yesterday

Principal Robotics Machine Learning Engineer

NewBe an early applicant North AmericaPrincipal
United States

Principal-level ML engineer at Apptronik who owns the end-to-end learned manipulation pipeline for the Apollo humanoid robot — from data engine design and simulation prototyping to training and on-robot deployment. Core stack: Python, C++, PyTorch, deep learning (CNNs, transformers, VLAs), computer vision, and simulators like IsaacSim/MuJoCo.

AI Automation Cloud Computer Vision C++ +11 skills
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Precision Medicine Group
1 views yesterday

Principal Clinical Data Scientist

Open 79d RemoteLATAMPrincipal H-1B sponsor history — This employer has had H-1B petitions approved by USCIS in the last five fiscal years, per the USCIS H-1B Employer Data Hub. The approval belongs to the employer and is not a commitment to sponsor this role.
Mexico

Leads clinical data review and cleaning for oncology trials, ensuring data integrity and regulatory compliance while coordinating cross-functional teams remotely.

Analytics Business Development Data Visualization GCP Process Improvement
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Precision Medicine Group
4 views yesterday

Principal Data Engineer

Open 79d RemoteAPACPrincipal H-1B sponsor history — This employer has had H-1B petitions approved by USCIS in the last five fiscal years, per the USCIS H-1B Employer Data Hub. The approval belongs to the employer and is not a commitment to sponsor this role.
India

Leads the design and operation of a cloud-native data platform for a healthcare analytics company, focusing on scalable infrastructure, data pipelines, and AI/ML enablement.

AI Airflow Analytics Automation AWS +34 skills
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Precision Medicine Group
1 views yesterday

Principal Central Monitor / Risk Manager

Open 31d APACPrincipal H-1B sponsor history — This employer has had H-1B petitions approved by USCIS in the last five fiscal years, per the USCIS H-1B Employer Data Hub. The approval belongs to the employer and is not a commitment to sponsor this role.
India

Oversee clinical-trial data quality by running risk-based monitoring, statistical reviews, and anomaly detection to ensure compliance and integrity across studies.

Data Quality GCP Statistics
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Precision Medicine Group
1 views yesterday

Principal Innovation Business Analyst

NewBe an early applicant RemoteUKPrincipal H-1B sponsor history — This employer has had H-1B petitions approved by USCIS in the last five fiscal years, per the USCIS H-1B Employer Data Hub. The approval belongs to the employer and is not a commitment to sponsor this role.
United Kingdom

The Principal Innovation Business Analyst acts as a bridge between clinical teams and technology partners to implement AI-enabled solutions and improve operational processes. The role involves gathering requirements, managing system implementations, and driving user adoption of tools like Microsoft Copilot within a clinical research environment.

Agentic AI AI Microsoft Copilot Process Improvement Requirements Gathering
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Precision for Medicine
4 views yesterday

Principal Clinical Data Scientist

Open 79d RemoteLATAMPrincipal H-1B sponsor history — This employer has had H-1B petitions approved by USCIS in the last five fiscal years, per the USCIS H-1B Employer Data Hub. The approval belongs to the employer and is not a commitment to sponsor this role.
Mexico

Leads clinical data review and cleaning for oncology trials, ensuring data integrity and regulatory compliance while coordinating cross-functional teams and managing study-specific scientific insights.

Analytics Business Development Data Visualization GCP Process Improvement
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Precision for Medicine
2 views yesterday

Principal Central Monitor / Risk Manager

Open 20d APACPrincipal H-1B sponsor history — This employer has had H-1B petitions approved by USCIS in the last five fiscal years, per the USCIS H-1B Employer Data Hub. The approval belongs to the employer and is not a commitment to sponsor this role.
India

Position Summary: The Principal Central Monitor (Risk Manager) serves as a strategic leader in driving data integrity, patient safety, and operational excellence across clinical development programs through advanced…

Data Quality GCP Statistics
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Precision for Medicine
2 views yesterday

Principal Innovation Business Analyst

NewBe an early applicant RemoteUKPrincipal H-1B sponsor history — This employer has had H-1B petitions approved by USCIS in the last five fiscal years, per the USCIS H-1B Employer Data Hub. The approval belongs to the employer and is not a commitment to sponsor this role.
United Kingdom

Principal Innovation Business Analyst bridging clinical teams and technology partners to implement AI-enabled solutions (e.g., Microsoft Copilot) and optimize clinical trial systems (CTMS, EDC, eTMF, RTMS) through requirements gathering, configuration, testing, and change management.

Agentic AI AI Microsoft Copilot Process Improvement Requirements Gathering
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Precision AQ
8 views yesterday

Principal Data Engineer

Open 79d RemoteAPACPrincipal
India

Principal Data Engineer builds and leads a cloud-native data platform for a healthcare analytics company, designing scalable pipelines, governance frameworks, and AI/ML integrations while mentoring teams.

AI Airflow Analytics Automation AWS +34 skills
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eProductivity Software
yesterday

Principal Engineer – Full Stack (.NET & Angular)

NewBe an early applicant APACPrincipal
India

The Principal Engineer leads architecture, design, and development of enterprise web applications using .NET/.NET Core, Angular, and SQL Server, while mentoring engineers and collaborating with product, QA, and DevOps teams to deliver secure, scalable software.

Agile Angular API Authentication Automation +26 skills
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Microsoft
yesterday

Principal UX Researcher

Open 37d On-siteNorth AmericaPrincipal
United States

Principal UX Researcher at Microsoft AI Monetization to lead mixed-methods research for AI-powered adtech products, shaping user-centered monetization experiences for billions.

Accessibility AI Information Architecture User Research
143K – 275K $
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Jeen AI
yesterday

Principal AI Architect

NewBe an early applicant On-siteMENAPrincipal
Israel

The Principal AI Architect at Jeen AI defines and leads the architectural vision for AI‑driven products, designing scalable, secure distributed systems on cloud and Kubernetes while guiding multiple R&D teams on generative AI, observability, and security standards.

Agentic AI AI Authentication AWS Azure +27 skills
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Santex
1 views yesterday

Principal Software Architect (Must: Go, Kafka & AWS)

Open 37d LATAMPrincipal
Argentina

Principal Software Architect designs and builds scalable backend systems using Go, Kafka, and AWS for a fintech travel/expense platform, ensuring reliability and performance.

AI AWS Cloud Containerization Design Patterns +5 skills
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Microsoft
1 views yesterday

Principal Software Engineer

Open 43d On-siteNorth AmericaPrincipal
United States

Principal Software Engineer at Microsoft builds and scales distributed cloud infrastructure to autonomously discover and validate vulnerabilities in Windows, leveraging AI-driven systems and Azure cloud services.

AI Automation Azure Azure DevOps Backbone.js +12 skills
143K – 275K $
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Microsoft
2 views yesterday

Principal Software Engineer

Open 31d On-siteNorth AmericaPrincipal
United States

Principal engineer defining hardware strategy and performance architecture for Microsoft 365, Copilot, and AI services, driving co-design across distributed systems and emerging hardware.

AI Azure Cloud C++ C# +5 skills
166K – 296K $
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Santex Group
yesterday

Principal Full-Stack Engineer (Must: Python & React)

NewBe an early applicant LATAMPrincipal
Argentina

Principal full-stack engineer building React 19 front-end experiences and Python data-processing pipelines for an AI-enriched enterprise capability map platform, including hierarchical data modeling, search/filtering, chatbot/AI service integration, and micro-frontends in a monorepo.

AI API Automation Data Modeling Gap Analysis +6 skills
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Santex Group
yesterday

Principal Full-Stack Engineer: AI‑Driven Knowledge Platform

NewBe an early applicant LATAMPrincipal
Argentina

Santex Group is hiring a Principal Full-Stack Engineer in Argentina to lead development of an AI-driven knowledge platform, bridging Python data processing with a React frontend. Day to day involves building APIs, integrating AI services, and shaping scalable frontend architecture for knowledge discovery.

AI API Python React
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hims-and-hers
2 views yesterday

Principal Data Engineer

Open 37d RemoteWorldwide, North AmericaFull-timePrincipal
United States

Principal Data Engineer at Hims & Hers designs and leads the company-wide data platform architecture, ensuring scalable, compliant, and cost-efficient data infrastructure for healthcare and wellness services using GCP, Kafka, BigQuery, and modern data stack tools.

AI Airflow Analytics AWS BigQuery +28 skills
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Clari + Salesloft
yesterday

Principal Software Engineer, AI

Open 79d LATAM, North AmericaPrincipal

Lead the AI Platform team to design and build the Context Layer—a data platform with knowledge graphs, RAG, vector search, and fine‑grained access control—while defining APIs/SDKs and collaborating with feature and data teams. Core tech includes Python/Java, knowledge graphs, vector databases, and retrieval systems.

Agentic AI Agile AI API Backbone.js +7 skills
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